Highly accurate protein structure prediction for the human proteome
This companion paper applied AlphaFold to predict structures for nearly the entire human proteome and 20 other key organisms, producing a large public database of predicted models. It assessed coverage and confidence across the human proteome, showing that a substantial fraction of residues could be modeled with high or very high confidence. The work created the AlphaFold Protein Structure Database, greatly expanding structural coverage beyond experimentally determined structures.